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Are You Looking for Benzene?



May. 15, 2023
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Benzene is a common organic compound. Small amounts of benzene are produced when materials containing carbon are burned incompletely. In recent decades, benzene has become increasingly popular mainly because it is an essential compound for making plastics. Learn more about benzene with Chemenu!


What is benzene?

Benzene, a hydrocarbon, the simplest aromatic hydrocarbon, is a sweet, flammable, carcinogenic, colorless, transparent liquid at room temperature with a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can be used as an organic solvent itself. Benzene has a ring system called benzene ring, and the structure of benzene ring after removing a hydrogen atom is called phenyl, which is expressed by Ph, so the chemical formula of benzene can also be written as PhH. benzene is a basic raw material of petrochemical industry, and its production and technical level of production is one of the signs of the development level of petrochemical industry in a country.



The manifestations of benzene poisoning

General symptoms of benzene poisoning.

Often have dizziness, headache, fatigue, insomnia, memory loss and other manifestations of neurological symptoms, in a month of re-examination, the white blood cell count fluctuates from 4 to 4.5 × 109 / L. Or platelet count fluctuates from 80 to 100 × 109 / L, with a tendency to bleeding.


Clinical manifestations of acute benzene poisoning.

1. Mild poisoning may include headache, dizziness, lacrimation, dry throat, cough, nausea and vomiting, abdominal pain, diarrhea, unsteady gait; purple groups of skin, nails and mucous membranes, acute conjunctivitis, tinnitus, photophobia, palpitations and pallor.


2. In moderate and severe poisoning, in addition to the aggravation of the above-mentioned symptoms, drowsiness, unresponsiveness, and confusion, there may be rapid coma, fine and rapid pulse, drop in blood pressure, generalized skin and mucous membrane cyanosis, increased respiration, convulsions, muscle tremors, and in some cases, agitation, euphoria, delirium and peripheral nerve damage, and even respiratory distress and shock.


3. Acute benzene poisoning is characterized by central nervous system depressive anesthesia, and systemic critical symptoms can occur, and the severe cases can die within minutes. It is reported that people inhale benzene vapor at a minimum concentration of 800 to 1000 mg/m3 for 4 to 6 hours.


Chronic benzene poisoning clinical manifestations.

Long-term low concentration inhalation of benzene fumes can cause chronic poisoning, common clinical manifestations include headache, dizziness, fatigue, dreaminess, memory loss and other neurasthenia syndrome and hematopoietic system changes.


Hematopoietic system changes are the characteristics of chronic benzene poisoning, which can have the following changes:


1. Abnormal blood picture, manifested as hypocytosis or complete blood cytopenia, early mostly seen only leukopenia.


2. Secondary aplastic anemia, manifested as complete blood cytopenia and bone marrow dysplasia.


3. Secondary myelodysplastic syndrome, manifesting as refractory anemia, iron-granulocytic anemia or with primitive cellular increase.


4. Secondary leukemia, mostly acute granulocytic leukemia.


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