Application of trifluoromethyl pyridine in insecticides and antagonists
2-Hydroxy-3-trifluoromethylpyridine is a widely used organic intermediate, not only for the synthesis of nicotinic insecticides, antagonist TRPV1, anti-androgen A52, but also for the synthesis of various drugs. 2-Hydroxy-3-trifluoromethylpyridine's physical and chemical information is shown as follows:
Physicochemical information of 2-hydroxy-3-trifluoromethylpyridine
White to off-white powder
Soluble in water, ethanol, ethyl acetate and other solvents
The quality specification of the product is shown as follows:
Quality specification of 2-hydroxy-3-trifluoromethylpyridine
1. Packaging and storage properties
1.1 Package: Fluorinated bottle, aluminum foil bag and cardboard drum
1.2 Storage: Keep the container airtight and store in a dry, ventilated and cool place.
2. Exposure hazard and control
2.1 Causes skin irritation and causes severe eye irritation.
2.2 Handle in a well-ventilated place. Wear suitable protective gear. Prevent dust from spreading. Wash hands thoroughly after handling.
3. Emergency treatment
3.1 First aid measures
Inhalation: Move the victim to fresh air, keep breathing open and rest. If feeling unwell seek medical attention/consultation.
Skin contact: Immediately remove/remove all contaminated clothing. Wash gently with plenty of soap and water. If skin irritation or rash occurs: Seek medical attention/consultation.
Eye contact: Wash carefully with water for several minutes. If convenient and easy to do, remove contact lenses. Continue washing. If eye irritation: Seek medical attention/consultation.
Ingestion: If discomfort occurs, seek medical attention/consultation. Rinse mouth.
Emergency responder protection: Rescuers need to wear personal protective equipment, such as rubber gloves and airtight goggles.
3.2 Fire Fighting Measures
Suitable extinguishing agents: dry powder, foam, fog water, carbon dioxide
Special hazards: Caution, burning or high temperature may decompose to produce toxic smoke.
Specific method: Extinguish the fire from upwind, choose the suitable fire extinguishing method according to the surrounding environment.
Non-relevant personnel should evacuate to a safe place.
Once the surrounding area is on fire: If safe, remove removable containers.
Special protective gear for firefighters: Always wear personal protective equipment when extinguishing a fire.
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